Are there any safety or placebo trials registered for the peptide BP-157?
I get this question often from clinicians and patients ask me what I mean when I say there is no human safety data.
There is no peer reviewed, publicly posted human safety data for BP–157 despite rapidly growing use spurred on by podcasts, gym talk, and social media.
Every 6 months or so I like to update my list of publications which include articles, book chapters, letters to the editor, and other references. Â My first co-authored paper, "The Buford Complex..." was published way back in 1994! Â So far in 2025, I have 4 articles/letters that have been published so far.
I stay current with the latest orthopedic and regenerative medicine research because I want my patients to have access to the best results as documented in research from around the world.  Whenever I get a chance, I like to contribute and participate to this rapidly growing field within orthopedics.
*The Las Vegas Regenerative Medicine and MSK Ultrasound Course*
*January 8-10, 2026 Virgin Hotel, Las Vegas*
We are back for our 18th year!
Hotel rooms in our block are $169 with NO resort fee and this hotel is part of the Hilton Curio Collection.....earn or use your Hilton points!
Thursday is a full day of practical regenerative medicine education. We review best practices based on the best data. We cover laser and shockwave and sustained acoustic medicine. We have live demos all afternoon!
Friday is upper extremity day. Lectures before lunch and 4 hours of upper extremity hands on after lunch with1 live model for every 2 trainees and 1 faculty for every 4 trainees.
Saturday is lower extremity and spine day with the same format!
The Problem?  There are no approved medical ozone devices or ozone therapies for ANY medical condition in the USA....so says the only regulatory authority....the FDA.
So, any clinic or doctor advertising ozone therapy or using an ozone device is likely using an adulterated and misbranded device and delivering an adulterated and misbranded drug.  And as noted in this recent Federal lawsuit against a Richmond doctor.....patients are being harmed.
So, at this point, regardless of anyone's opinion on the medical benefits of ozone therapy.....we can't do it legally in the USA at the present time.
There is a great orthopedic meeting going on right now in Acapulco, Mexico!
This is the 29th annual AMECRA meeting which is an international meeting focused on arthroscopy and arthroplasty and reconstructive surgery.
The thought leaders in orthopedics and regenerative medicine in Mexico are here and I am looking forward to learning their approaches to helping patients with orthopedic challenges.
Can a stem cell (bone marrow concentrate) injection outperform a PRP injection in the small joints of the hand/wrist?
It's a question I often get asked.....with such a small volume injection is there still a potential benefit of doing BMC over PRP?
Well, this surgeon had PRP before we met 3 years ago and he did feel PRP worked better and lasted longer than steroid. Then we met and he wanted to try BMC. Fast forward 3 years and he has done significantly better ...about 3x longer benefit.... with BMC versus PRP.
I get that this is a case study and a patient testimonial...but it is still true and something to consider when advising patients about the potential outcomes of out orthobiologic options!
A frozen shoulder is simply a shoulder that does not have normal motion. Â Usually a frozen shoulder is painful, especially when the limits of the range of motion are reached.
The most common reason why this happens is from minor shoulder trauma. Â Sometimes it can happen after a surgical procedures. And sometimes it can happen without any real history of an injury at all! Â
At Texas Orthobiologics we have been helping patients with challenging frozen shoulder symptoms for over 25 years. Â Over that time we have developed more nonsurgical ways, including the use of regenerative medicine techniques in the office, to shorten the impact of frozen shoulders for our patients.
Regenerative medicine and ultrasound use are growing within orthopedics! Last month at the 2025 annual Arthroscopy Association Of North America meeting (AANA) I lectured on regenerative medicine topics, led the MSK ultrasound training course, and had an all around fantastic time connecting with colleagues and spreading the latest evidence based info in our field.
At Texas Orthobiologics we currently specialize in using platelet rich plasma (PRP) and bone marrow concentrate (BMC-stem cells) as our two primary orthobiologics. Â We also use other non-surgical techniques to benefit our patients and keep them living their best lives without surgery!
Patient Testimonial!
4.5 years after a bone marrow concentrate injection for her knee arthritis! Results vary of course.
This is a nonsurgical option that may not eliminate surgery but for so many of our patients at Texas Orthobiologics this is a great non surgical option that minimizes their arthritis pain for years!
