*Shouldn't we all want to know the #PRP and BMC/Stem Cell data?*
I confess I have a type A desire to know how things work and why! Especially with human biology, orthopedic surgery, and regenerative medicine topics.
For that reason, I do the best I can to quantify, describe and track any procedures/surgeries/interventions so that on the off chance they work....I can do it again for the next person. At Texas Orthobiologics we use a hematology machine to quantify the PRP doses and concentrations we are giving patients. We have an abundance of high level clinical data giving us dosing parameters (from hematology machines) for various orthopedic conditions. It isn't perfect but it is the best we can do in the office at the point of care. Likewise, getting a cell counter so we can determine a total nucleated cell count for a bone marrow concentrate(BMC) procedures make sense. But TNCC also has limitations.....TNCC doesn't directly correlate with the actual MSC or HSC count....but it is a good proxy same day metric for quantifying BMC procedures. Three papers out of India this year already have looked at BMC data for knee osteoarthritis using a total nucleated cell count as the metric for dosing evaluation. Below is today's PRP printout from the Horiba Micros ES 60. 60cc of blood--->6 cc of PRP. 6x concentration. Platelet count from 288 to 1707 with a lowered granulocyte percentage in the PRP (ie. LP-PRP)
DOSE? 10.24 Billion platelets in 6 cc.
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